首页> 外文OA文献 >Rationale and design of DUAL study: Doxycycline to Upgrade response in light chain (AL) amyloidosis (DUAL): A phase 2 pilot study of a two-pronged approach of prolonged doxycycline with plasma cell-directed therapy in the treatment of AL amyloidosis

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Rationale and design of DUAL study: Doxycycline to Upgrade response in light chain (AL) amyloidosis (DUAL): A phase 2 pilot study of a two-pronged approach of prolonged doxycycline with plasma cell-directed therapy in the treatment of AL amyloidosis

机译：DUaL研究的基本原理和设计：强力霉素可以提高轻链（aL）淀粉样变性（DUaL）的反应：使用浆细胞定向治疗延长强力霉素双管齐下治疗aL淀粉样变性的2期试验研究

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Anita D'Souza; Kathryn Flynn; Saurabh Chhabra; Binod Dhakal; Mehdi Hamadani; Kirsten Jacobsen; Marcelo Pasquini; Dorothee Weihrauch; Parameswaran Hari;
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1. Rationale and design of DUAL study: Doxycycline to Upgrade response in light chain (AL) amyloidosis (DUAL): A phase 2 pilot study of a two-pronged approach of prolonged doxycycline with plasma cell-directed therapy in the treatment of AL amyloidosis [J] . Anita DSouza, Kathryn Flynn, Saurabh Chhabra, Contemporary Clinical Trials Communications . 2017,第2期

机译：DUAL研究的基本原理和设计：强力霉素提高轻链（AL）淀粉样变性病（DUAL）的反应：一项延长的多西环素与浆细胞导向疗法在AL淀粉样变性治疗中的两管齐下的2期试验研究
2. Adjuvant Doxycycline to Enhance Anti-Amyloid Effects: Results from the DUAL (Doxycycline to Upgrade response in AL amyloidosis) Study [J] . DSouza Anita, Flynn Kathryn E., Dhakal Binod, Blood: The Journal of the American Society of Hematology . 2018,第NovaelaTreatmentAppr期

机译：佐剂毒素增强抗淀粉样蛋白：双重（糖苷霉素在Al淀粉样症升级的反应）研究结果
3. Isolation and biochemical characterization of plasma monoclonal free light chains in amyloidosis and multiple myeloma: a pilot study of intact and truncated forms of light chains and their charge properties. [J] . Kaplan B, Ramirez-Alvarado M, Dispenzieri A, Clinical chemistry and laboratory medicine: CCLM . 2008,第3期

机译：淀粉样变性和多发性骨髓瘤中血浆单克隆游离轻链的分离和生化特征：完整和截短形式的轻链及其电荷性质的初步研究。
4. THE INHIBITORY Fcy-RECEPTOR MB (CD32B) IS HIGHLY EXPRESSED ON CLONAL PLASMA CELLS FROM PATIENTS WITH SYSTEMIC LIGHT-CHAIN (AL) AMYLOIDOSIS AND PROVIDES A TARGET FOR MONOCLONAL ANTIBODY THERAPY [C] . P. Zhou, A B Olshen, E Bonvini, International Symposium on Amyloidosis . 2008

机译：抑制性FCY-受体MB（CD32B）对来自全身轻链（AL）淀粉样蛋白症患者的克隆血浆细胞高度表达，并为单克隆抗体治疗提供靶标
5. The Efficacy of ACT With Individuals With Intellectual Disability: A Pilot Study on the Role of Intelligence and Language in Treatment Response. [D] . Cofer, Katherine. 2016

机译：ACT对智障人士的功效：智力和语言在治疗反应中的作用的初步研究。
6. Rationale and design of DUAL study: Doxycycline to Upgrade response in light chain (AL) amyloidosis (DUAL): A phase 2 pilot study of a two-pronged approach of prolonged doxycycline with plasma cell-directed therapy in the treatment of AL amyloidosis [O] . Anita DSouza, Kathryn Flynn, Saurabh Chhabra, 2017

机译：DUAL研究的基本原理和设计：强力霉素提高轻链（AL）淀粉样变性病（DUAL）的反应：延长的多西环素与浆细胞导向疗法在AL淀粉样变性治疗中的两管齐下的2期试验研究
7. A randomized, comparative study of dual therapy (doxycycline–rifampin) versus triple therapy (doxycycline–rifampin–levofloxacin) for treating acute/subacute brucellosis [O] . Ahmad Hasanain, Reem Mahdy, Asmaa Mohamed, 2016

机译：双重疗法（强力霉素 - 利福平）与三联疗法（强力霉素 - 利福平 - 左氧氟沙星）治疗急性/亚急性布鲁氏菌病的随机对照研究

Rationale and design of DUAL study: Doxycycline to Upgrade response in light chain (AL) amyloidosis (DUAL): A phase 2 pilot study of a two-pronged approach of prolonged doxycycline with plasma cell-directed therapy in the treatment of AL amyloidosis

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